Prednisone (Prednisone) side effects
Please see general statement regarding side effects.
Side effects may include: euphoria, insomnia, mood changes, personality changes, psychotic behavior, severe depression, or worsening of any existing emotional instability
At a high dosage, prednisone may cause fluid retention and high blood pressure.
If prednisone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining prednisone with the following: amphotericin B, anticholinesterase agents (such as neostigmine, pyridostigmine), aspirin and other nonsteroidal anti-inflammatory agents (NSAIDs), barbiturates, blood thinners (such as warfarin), bupropion, carbamazepine, cholestyramine, cyclosporine, digitalis, estrogen drugs, fluoroquinolones (such as ciprofloxacin, levofloxacin), indinavir, insulin, isoniazid, itraconazole, ketoconazole, macrolide antibiotics (such as erythromycin), birth control pills, oral diabetes medication, phenobarbital, phenytoin, potent diuretics, quetiapine, rifampin, ritonavir, thalidomide, troleandomycin, and vaccines.
The effects of prednisone during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take two doses at once.
Do not take prednisone if you have ever had an allergic reaction to it or have a fungal infection.