Ryzolt (Tramadol HCl)
Ryzolt is an opioid painkiller that is used to treat moderate to moderately severe long-term pain that requires treatment for an extended period.
Ryzolt can cause seizures. The risk is greater if you have a history of seizures, are suffering from alcohol or drug withdrawal (abrupt discontinuation or a decrease in the dose of medicines, recreational drugs, or alcohol you take), or nervous system infections. Your risk of seizures may also be increased if you are taking monoamine oxidase inhibitors (MAOIs), a class of medicines used to treat depression and other psychiatric conditions (such as phenelzine); antidepressant/psychiatric medicines in classes known as selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine or paroxetine), selective norepinephrine reuptake inhibitors (SNRIs) (such as venlafaxine), or tricyclic antidepressants (TCAs) (such as amitriptyline); certain migraine products (such as sumatriptan); or other opioids.
You can develop a serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) when you are using Ryzolt, especially if you take it in combination with MAOIs, SSRIs, SNRIs, certain migraine products, or certain antidepressants. Symptoms can include hallucinations, increase in your heart rate, fever, incoordination, and/or stomach problems. Contact your doctor immediately if you develop any of these signs or symptoms.
Anaphylactoid reactions (a serious and rapid allergic reaction that may result in death if not immediately treated) can occur. Contact your doctor or get emergency help immediately if you experience difficulty breathing; swelling of the throat, tongue, or mouth; or hives.
Taking Ryzolt can also lead to abuse, addiction, and dependence.